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KMID : 0360120110330050420
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
2011 Volume.33 No. 5 p.420 ~ p.424
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Guided Bone Regeneration Using a Putty-type Demineralized Bone Matrix: Case Report
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Jang Han-Seung
Kim Su-Gwan
Moon Seong-Yong
Oh Ji-Su
Park Jin-Ju
Jeong Mi-Ae
Yang Seok-Jin
Jung Jong-Won
Kim Jeong-Sun
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Abstract
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Allomatrix (Wright Medical Tech, Inc., Arlington, Tenn, USA), is a newly designed, injectable putty with a reliable demineralized bone matrix (DBM), derived from human bone. The compound contains 86% DBM and other bone growth factors such as bone morphogenic protein (BMP)-2, BMP-4, insulin-like growth factor (IGF)-1, and transforming growth factor (TGF)-beta1. It has excellent osteoinduction abilities. In addition, DBM is known to have osteoconduction capacity as a scaffold due to its collagen matrix. This product contains a powder, which is a mix of DBM and surgical grade calcium sulfate as a carrier. A practitioner can blend the powder with calcium sulfate solution, making a putty-type material which has the advantages of ease of handling, better fixation, and no need for a membrane, because it can function as membrane itself. This study reports the clinical and radiographic results of various guided bone regeneration cases using Allomatrix, demonstrating its strong potential as a graft material.
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KEYWORD
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Bone morphogenic protein, Demineralized bone matrix, Growth factor, Osteoinduction
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